KM 11060

Product Name: KM 11060
CAS No.: 774549-97-2
Chemical Name: KM 11060
Synonyms: KM 11060;KM11060;KM-11060;CFTR-F508del Corrector, KM11060;7-CHLORO-4-(4-(4-CHLOROPHENYLSULFONYL)PIPERAZIN-1-YL)QUINOLINE;7-CHLORO-4-[4-[4-CHLOROPHENYL)SULFONYL]-1-PIPERAZINYL]QUINOLINE;Quinoline, 7-chloro-4-[4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl]-;KM 11060,inhibit,KM11060,Inhibitor,Autophagy,Cystic fibrosis transmembrane conductance regulator,CFTR,KM-11060
CBNumber: CB02446666
Molecular Formula: C19H17Cl2N3O2S
Formula Weight: 422.33
MOL File: 774549-97-2.mol

More

Less

KM 11060 Property

storage temp.: Store at RT
solubility: Soluble to 100 mM in DMSO and to 10 mM in ethanol
form: Powder

More

Less

Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 45

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 23481
Product name: KM 11060
Purity: ≥98%
Packaging: 5mg
Price: $90
Updated: 2024/03/01

Cayman Chemical

Product number: 23481
Product name: KM 11060
Purity: ≥98%
Packaging: 10mg
Price: $161
Updated: 2024/03/01

Cayman Chemical

Product number: 23481
Product name: KM 11060
Purity: ≥98%
Packaging: 25mg
Price: $355
Updated: 2024/03/01

Cayman Chemical

Product number: 23481
Product name: KM 11060
Purity: ≥98%
Packaging: 50mg
Price: $444
Updated: 2024/03/01

Tocris

Product number: 3143
Product name: KM11060
Purity: ≥98%(HPLC)
Packaging: 50
Price: $483
Updated: 2021/12/16

More

Less

KM 11060 Chemical Properties,Usage,Production

Uses

KM 11060 is a small molecular corrector of F508del CFTR trafficking, which has potential application in cystic fibrosis therapeutics.

Biological Activity

Corrects F508del-CFTR trafficking; increases the amount of functional CFTR at the plasma membrane (~75%). Shown to inhibit PDE5 activity.

KM 11060 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

KM 11060 Suppliers

China 58 India 1 United Kingdom 1 United States 11 Global 71

More

Less

View Lastest Price from KM 11060 manufacturers

Career Henan Chemical Co

Product: KM 11060 774549-97-2
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 20kg
Release date: 2019-12-23

774549-97-2, KM 11060Related Search:

TPP Benzyl alcohol 4-Chloroaniline Sulfenone 4'-Hydroxyacetophenone Chlorobenzene 7-CHLORO-4-N,N-DIMETHYLAMINO-QUINOLINE 1-(4-Pyridyl)piperazine 4-(2-AMINOETHYLAMINO)-PYRIDINE HYDROCHLORIDE KM 11060 7-Chloro-4-piperazinoquinoline 4-(2-AMINOETHYL)AMINOQUINOLINE 7-CHLORO-4-(4-[(4-CHLORO-3-NITROPHENYL)SULFONYL]PIPERAZINO)QUINOLINE 4-(2-AMINOETHYL)AMINO-7-CHLOROQUINOLINE 4-PIPERAZIN-1-YL-QUINOLINE 1-(4-CHLORO-BENZENESULFONYL)-PIPERAZINE

7-CHLORO-4-(4-(4-CHLOROPHENYLSULFONYL)PIPERAZIN-1-YL)QUINOLINE

7-CHLORO-4-[4-[4-CHLOROPHENYL)SULFONYL]-1-PIPERAZINYL]QUINOLINE

KM 11060

CFTR-F508del Corrector, KM11060

KM11060;KM-11060

Quinoline, 7-chloro-4-[4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl]-

KM 11060,inhibit,KM11060,Inhibitor,Autophagy,Cystic fibrosis transmembrane conductance regulator,CFTR,KM-11060

774549-97-2